crohn’s disease
Conditions
Interventions
Normal control group:None
Intervention Group A:Electroacupuncture treatment
Intervention Group B:Drug therapy
Sponsors
The First Affiliated Hospital of Zhejiang Chinese MedicalUniversity(Zhejiang Provincial Hospital of Chinese Medicine)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for patients: 1. Confirmed diagnosis of CD by colonoscopy or clinical diagnosis; 2. Aged 18-60 years, right-handed; 3. Patients in the active phase, with pain that is new onset and untreated; 4. Signed informed consent form. Inclusion criteria for volunteers: 1. Exclusion of gastrointestinal diseases; 2. Aged 18-60 years, right-handed; 3. Willing to participate in the study and signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Other gastrointestinal diseases or other diseases causing abdominal pain; 2. Organic brain lesions, mental disorders; 3. Use of opioids, corticosteroids, or psychotropic drugs in the past three months; 4. Claustrophobia or individuals with metal implants in their bodies; 5. Women who are menstruating, pregnant, or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visceral Pain Questionnair Score;Visual Analogue Scale Score;Corticotropin-Releasing Hormone;Adrenocorticotropic Hormone;Corticosterone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting-State Functional Magnetic Resonance Imaging;prefrontal metabolites; | — |
Countries
China
Contacts
Public ContactFeini Zhou
The First Affiliated Hospital of Zhejiang Chinese MedicalUniversity(Zhejiang Provincial Hospital of Chinese Medicine)
Outcome results
None listed