Preoperative Sedation and Analgesia for Lung Nodule Localization
Conditions
Interventions
Group of dexmedetomidine hydrochloride nasal spray:Intranasal administration of dexmedetomidine hydrochloride nasal spray
Group of sodium chloride:0.9% sodium chloride nasal spray
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years; 2.ASA Physical Status I–III; 3.BMI18.5~29.9kg/m^2; 4.Undergoing thoracic surgery under general anesthesia; 5.Possesses good comprehension and verbal communication skills, able to cooperate with sedation and pain assessments; 6.Signed informed consent form;
Exclusion criteria
Exclusion criteria: 1.Known allergy to dexmedetomidine or related drugs; 2.Severe nasal diseases (such as severe nasal mucosal congestion, edema, sinusitis, or nasal polyps); 3.Severe cardiac, pulmonary, hepatic, or renal dysfunction present preoperatively; 4.Severe psychiatric disorders or cognitive impairments; 5.Long-term preoperative use of sedative or analgesic drugs, or a history of substance abuse; 6.Pregnant or breastfeeding women; 7.Other conditions deemed unsuitable for participation in this study by the investigator;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of moderate pain based on the NRS score for movement-related pain after pulmonary nodule localization in patients; | — |
Countries
China
Contacts
Public ContactChen Shaomu
The First Affiliated Hospital of Soochow University
Outcome results
None listed