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Differences in prognosis between different subtypes of lung adenocarcinoma

A retrospective study on the differences in postoperative prognosis among different subtypes of lung adenocarcinoma

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109210
Enrollment
Unknown
Registered
2025-09-15
Start date
2025-10-08
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung adenocarcinoma

Interventions

High-risk:Lung adenocarcinoma tissue contains high-risk subtype components.
Low-risk:Lung adenocarcinoma tissue contains high-risk subtype components.

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients are aged 18 years or older and under 75 years (inclusive of 18 and 75 years); 2. Postoperative pathological examination confirms a definitive diagnosis of lung adenocarcinoma, with clear histological subtype classification (consistent with lepidic, acinar, papillary, micropapillary, solid, or mucinous patterns); 3. Patients have undergone radical surgical treatment for lung adenocarcinoma (e.g., lobectomy, segmentectomy, and mediastinal lymph node dissection), with complete surgical records; 4. Clinical and follow-up data are comprehensive, including preoperative baseline information, postoperative treatment regimens, pathology reports, and survival status follow-up data; 5. No history of other malignancies.

Exclusion criteria

Exclusion criteria: 1.The pathological diagnosis is unclear or the subtype classification is vague, and it cannot be accurately classified. 2.Received palliative surgery or only biopsy, and did not meet the criteria for radical surgery. 3.Serious lack of clinical data or follow-up data (such as incomplete key prognostic indicators and treatment information). 4.Death due to non-tumor-related factors (such as serious complications, accidents) in the short term after surgery (such as within 1 month). 5.Combined with serious underlying diseases (such as severe heart, liver and kidney failure) may significantly affect survival assessment.

Design outcomes

Primary

MeasureTime frame
Progression-free survival;Time and site of first recurrence after surgery;

Secondary

MeasureTime frame
Postoperative survival;

Countries

China

Contacts

Public ContactLi Jue

West China Hospital of Sichuan University

lijue16@163.com+86 28 85422114

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026