Skip to content

The effect of microwave ablation on immune function in patients with malignant liver tumors

The effect of microwave ablation on immune function in patients with malignant liver tumors

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109205
Enrollment
Unknown
Registered
2025-09-15
Start date
2025-09-30
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malignant liver tumors

Interventions

Microwave ablation treatment group:NA

Sponsors

China-Japan Union Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Primary liver cancer: percutaneous puncture pathological diagnosis; Diagnosed according to the "Diagnosis and Treatment Standards for Primary Liver Cancer" without pathological patients. Metastatic liver cancer: percutaneous puncture pathological diagnosis; Non pathological patients who meet the diagnosis criteria for metastatic liver cancer in the "Diagnosis and Treatment Standards for Primary Liver Cancer".; (2) The diameter of the lesion is less than 5cm. (3) Liver cancer lesions are suitable for microwave ablation treatment; (4) There is no gender or age limit.

Exclusion criteria

Exclusion criteria: (1) Tumors cannot be completely ablated by microwave in one go; (2) During the study, severe liver and kidney dysfunction, coagulation disorders, and immune system diseases were combined; (3) Received surgery, intervention, radiotherapy, chemotherapy, and immune enhancers within one month before and after ablation treatment; (4) I am currently participating in other clinical studies.

Design outcomes

Primary

MeasureTime frame
heat shock protein 70;heat shock protein 90;

Secondary

MeasureTime frame
Interferon ?;Interleukin 2;Interleukin 6;Interleukin 8;Interleukin 10;Interleukin 12;Interleukin 22;Tumor necrosis factor a;CD3+T cell levels;CD4+T cell levels;CD8+T cell levels;

Countries

China

Contacts

Public ContactGuoqing Sui

China-Japan Union Hospital of Jilin University

suiguoqing@jlu.edu.cn+86 135 0432 4665

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026