herpes zoster
Conditions
Interventions
the control group (Group C) :According to the standard pharmacological treatment in pain management, the patient is prescribed pregabalin (one capsule morning and evening), oxycodone/acetaminophen (on
the dexmedetomidine group (Group D).:According to the standard pharmacological treatment in the pain department, the patient is prescribed oral pregabalin (one capsule twice daily, morning and evening
Sponsors
Jiangsu Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18-80 years, regardless of gender. (2) Clearly diagnosed with thoracic and back herpes zoster neuralgia (HZN), accompanied by obvious allodynia and hyperalgesia. (3) Sleep is affected (VAS score = 4 points).
Exclusion criteria
Exclusion criteria: (1) A history of chronic rhinitis. (2) Preoperative sick sinus syndrome, severe sinus bradycardia (heart rate < 50 beats/min), second-degree or higher atrioventricular block, permanent pacemaker implantation, severe heart failure, or ejection fraction < 30%. (3) A history of cerebral hemorrhage or stroke, and insufficiency of important organ functions such as heart, brain, and kidney (Child-Pugh grade B or C, chronic kidney disease stage 3-5). (4) A history of taking sedatives, antidepressants, or other psychotropic drugs for depression or sleep disorders. (5) Allergies to the study drugs. (6) Severe dementia, low cognitive function, language disability, severe hearing or visual impairment, mental disorders, coma, or any other diseases that would hinder the completion of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Sleep Time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Deep Sleep Time;Light Sleep Time;Rapid Eye Movement Sleep Time;Number of Awakenings;Visual analogue scale; | — |
Countries
China
Contacts
Public ContactSun Xiaodi
Jiangsu Provincial People's Hospital
Outcome results
None listed