Acute Myocardial Infarction (AMI)
Conditions
Interventions
Reactive Oxygen Species (ROS) High-Level Group (Group T3):None
Reactive Oxygen Species (ROS) Medium-Level Group (Group T2):None
Reactive Oxygen Species (ROS) Low-Level Group (Group T1):None
Sponsors
The First Hospital Of Jiaxing
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-80 years old; 2. Diagnosed with Acute Myocardial Infarction (AMI) and treated with Percutaneous Coronary Intervention (PCI); 3. Informed consent signed by the patient or their legal representative.
Exclusion criteria
Exclusion criteria: 1. Complicated with other severe cardiovascular diseases such as cardiomyopathy and valvular heart disease; 2. Severe hepatic and renal insufficiency (ALT/AST > 3 times the upper limit of normal, creatinine clearance < 30 ml/min); 3. A history of major surgery or trauma within the past 6 months, or malignant tumor (with an expected survival time < 1 year); 4. Inability to cooperate with follow-up, or presence of mental illness and cognitive impairment; 5. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major Adverse Cardiovascular Events (MACE: reinfarction, heart failure, stroke, cardiogenic death);Reactive Oxygen Species (ROS) Level (including O2-, H2O2) , Cellular Metabolic Activity (CMA) Indicators (protein synthesis efficiency, ATP production rate, enzyme catalytic activity); | — |
Secondary
| Measure | Time frame |
|---|---|
| Minor Adverse Cardiovascular Events (angina pectoris, coronary slow flow/no-reflow); | — |
Countries
China
Contacts
Public ContactZhai Changlin
The First Hospital Of Jiaxing
Outcome results
None listed