Tuberculous Lymphadenitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18~60 years old; 2. Patients with lymph node tuberculosis who are planned to be surgically removed; 3. Signed informed consent and agreed to participate in follow-up.
Exclusion criteria
Exclusion criteria: 1. Combined with severe infection; 2. HIV-infected patients with a family history of immunodeficiency; 3. Long-term use of immunosuppressants, post-organ transplantation, and malignant tumors; 4. Pregnancy or lactation; 5. Difficulty in follow-up or refusal of participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The differences in transcriptome expression profiles among different pathological classifications of lymph node tuberculosis lesions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bacterial load in lymph nodes;Pathological-related indicators;Imaging indicators;Measurement of drug concentrations in blood and tissues;Post-operative health status assessment;Differential gene expression levels; | — |
Countries
China
Contacts
Beijing Chest Hospital, Capital Medical University