Acute Cerebral Infarction
Conditions
Interventions
The treatment group:The treatment group was additionally given remote ischemic conditioning (RIC) on the basis of conventional treatment. Specifically, a blood pressure cuff was applied to the unaffec
inflation of the cuff for 5 minutes followed by deflation to restore blood flow for 5 minutes constituted one cycle. One treatment session included 5 cycles, totaling 50 minutes. The pressure applied
The control group:The control group was additionally given sham RIC on the basis of conventional treatment, which meant the same 50-minute treatment cycle per session, but the pressure applied during
Sponsors
The First People's Hospital of Hefei
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years; 2. Meet the diagnostic criteria for acute ischemic stroke, with new infarct lesions on cranial magnetic resonance diffusion-weighted imaging (DWI); 3. Onset time less than 72 hours; 4. National Institutes of Health Stroke Scale (NIHSS) score <= 6.
Exclusion criteria
Exclusion criteria: 1. Those receiving intravenous thrombolysis or endovascular treatment; 2. Those with infection or swelling in the upper limb; 3. Those who cannot complete the appropriate treatment for remote ischemia and have poor compliance; 4. Those with cerebral hemorrhage; 5. Those with subclavian steal syndrome; 6. Those with malignant tumors and serious diseases, such as severe heart failure, renal failure, liver failure, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale score on day 90 of the disease course;The detection indicators of bilateral middle cerebral arteries via transcranial Doppler ultrasound on admission and on the 7th day of the disease course; | — |
Secondary
| Measure | Time frame |
|---|---|
| NHISS scores on admission and on the 7th day of the disease course; | — |
Countries
China
Contacts
Public ContactBin Dong; Jiani Tan
The Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei)
Outcome results
None listed