Osteocytes under the condition of iron overload by Wnt/ß-catenin signaling pathways regulating role in the differentiation of bone marrow stromal cells osteogenesis mechanism

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500109185

Enrollment

Unknown

Registered

2025-09-15

Start date

2025-09-15

Completion date

Unknown

Last updated

2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporosis

Interventions

Healthy young adults:Control group, no intervention

Young adults with osteoporosis:None

Healthy older adults:None

Elderly adults with osteoporosis:None

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Healthy young people caused by traffic accident, young people with osteoporotic cervical spondylosis, healthy elderly people and elderly people with osteoporosis, who met the surgical indications for cervical spine diseases and had no relevant contraindications, including anterior surgery (such as ACDF, ACCF, ACDR) and posterior surgery (such as spinal canal decompression, bone graft fusion and internal fixation), agreed to sign the informed consent.

Exclusion criteria

Exclusion criteria: Did not meet the inclusion criteria and did not consent to participate in the study.

Design outcomes

Primary

Measure	Time frame
Gene and protein expression of ferroptosis in cells;	—

Countries

China

Contacts

Public ContactXiang Hong

Affiliated Yongchuan Hospital of Chongqing Medical University

3241669516@qq.com+86 177 8307 9528

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026