Perioperative stroke
Conditions
Interventions
Intervention Group:Intervention group patients will follow routine solid food fasting (fasting from 8 hours preoperatively) while relaxing clear liquid intake restrictions (no drinking from 2 hours pr
Control Group:Conventional preoperative fasting strategy will be adopted according to current departmental routine management. In brief, solid food fasting begins at least 8 hours preoperatively. For
Sponsors
The First Affiliated Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Age >= 18 years 2) Scheduled for first-time elective neurointervention for cerebral aneurysm under general anesthesia 3) ASA physical status I-III 4) No significant neurological deficits preoperatively (mRS score 0-1) 5) Able to drink water orally without swallowing difficulties 6) Written informed consent obtained
Exclusion criteria
Exclusion criteria: 1) Participation in another interventional clinical trial 2) Emergency surgery or preoperative aneurysm rupture 3) High-risk factors for aspiration 4) Pregnancy 5) Dysphagia or impaired consciousness 6) Severe comorbidities (uncontrolled cardiopulmonary disease or renal insufficiency)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post-operative stroke; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in cerebral perfusion indicated by MR;Stroke with clinical symptoms;Cognitive function changes;QoR-15 scores;Creatinine change; | — |
Countries
China
Contacts
Public ContactWenqi Huang
The First Affiliated Hospital, Sun Yat-sen University
Outcome results
None listed