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Clinical observation on the efficacy of polylactic acid microneedles combined with supramolecular lactic acid in the treatment of acne

Clinical observation on the efficacy of polylactic acid microneedles combined with supramolecular lactic acid in the treatment of acne

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109165
Enrollment
Unknown
Registered
2025-09-14
Start date
2025-09-15
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne

Interventions

Divide into a group, use their own face before and after comparison:MS-I type (lactic acid concentration 40%, 2g), HS-1 type (lactic acid concentration 80%, 2g)

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1.The patient is judged by two deputy chief dermatologists or above to meet the clinical diagnosis of facial grade II acne or above. 2.Study participants had not taken any treatment for facial acne in the 3 months prior to enrollment. 3.Age range: 18-35 years old, gender not limited. 4.The study sites were not associated with other skin diseases. 5.The patients were willing to accept treatment, observation and various examinations, had good compliance, and signed the informed consent before enrollment. 6.Study participants agreed not to participate in other intervention studies during the treatment period.

Exclusion criteria

Exclusion criteria: 1.Suffering from endocrine system diseases or autoimmune diseases. 2.Pregnant or breastfeeding women. 3.Suffering from malignant tumors or severe heart, liver, lung, or kidney diseases. 4.Any treatment for improving facial acne, such as laser, intense pulsed light, chemical peel, oral or topical medication, etc., has been received within the past 3 months. 5.Any unstable condition or condition that may endanger the patient's safety and compliance with the study, such as intellectual disability, schizophrenia and other severe mental illnesses, inability to understand, read and fill out the patient self-assessment scale, and inability to cooperate with treatment and examination. 6.Have a history of allergy to acid brushing or cannot tolerate acid brushing treatment. 7.Those who work outdoors during the study period or are unable to strictly protect themselves from the sun. 8.The face is accompanied by skin infections such as herpes simplex, common warts, or local trauma. 9.Those who are positive for dermatographism or have sensitive facial skin.

Design outcomes

Primary

MeasureTime frame
Comprehensive acne grading system scale and GASS scoring method;

Countries

China

Contacts

Public ContactRuixing Yu

China-Japan Friendship Hospital

yuruixing521@163.com+86 185 1169 8131

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026