epilepsy
Conditions
Interventions
Observation group:None
Sponsors
Xuanwu Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Clinical data of epilepsy patients treated in the Functional Neurosurgery Department of Xuanwu Hospital, Capital Medical University, or Beijing Tiantan Hospital affiliated with Capital Medical University from 2018 to 2026; 2. The age limit for data collection is set for those aged 4 and above, and under 60 (based on the FDA's age limit for Vagus Nerve Stimulation (VNS) being at least 4 years old, and 18 years for Responsive Neurostimulation (RNS) established in 2013; considering that the minimum age limit may be relaxed in the future, it is necessary to adapt the predictive model to the EEG patterns of children); 3. The types of epilepsy fall into the following categories: (1) Seizures originating in the temporal lobe; (2) Seizures originating in the motor cortex; (3) Seizures originating in the parietal-occipital lobe; (4) Epilepsy secondary to tumors or other focal pathological changes; 4. Patients who underwent routine pre-surgical evaluations for epilepsy during hospitalization, and underwent necessary imaging and electroencephalographic examinations with accessible raw data. Specifically, imaging examinations included structural imaging of the head using MRI (three-dimensional magnetization prepared rapid gradient echo sequence 3D MP-RAGE), and post-electrode implantation thin-cut CT (for locating electrode positions); other imaging examinations included Magnetoencephalography (MEG) and Positron Emission Tomography (PET) which served as the basis for patient grouping in this study; electroencephalographic examinations included scalp electroencephalography (EEG), intraoperative subdural electrode monitoring EEG recording (ECoG), and stereotactic electroencephalography (SEEG).
Exclusion criteria
Exclusion criteria: 1. The patient's EEG data was not fully preserved, and the number of recorded seizure EEG data was less than three times. 2. The patient terminated the surgical treatment for various reasons. 3. Other researchers considered themselves ineligible to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Event-related potential waveform differences;Task-related time-frequency characteristics;Functional connectivity; | — |
Countries
China
Contacts
Public ContactTao Yu
Xuanwu Hospital, Capital Medical University
Outcome results
None listed