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A study on the clinical characteristics and influencing factors of adverse events associated with immune checkpoint inhibitors

A study on the clinical characteristics and influencing factors of adverse events associated with immune checkpoint inhibitors

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109148
Enrollment
Unknown
Registered
2025-09-12
Start date
2025-05-19
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal tumours, melanoma

Interventions

Case group (irAEs group):None
Control group (non-irAEs group):None

Sponsors

Shanghai Tenth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age 18 or above, gender is not limited 2. Completed at least 1 cycle of ICI treatment 3. histopathologically diagnosed with advanced solid tumour 4. have complete baseline data (e.g. age, gender, past medical history, treatment regimen, occurrence of irAEs) 5. Follow-up time = 3 months

Exclusion criteria

Exclusion criteria: 1. Previous severe autoimmune or other diseases (e.g., systemic lupus erythematosus, myasthenia gravis, severe lesions of other organs) 2. Use of immunosuppressants or glucocorticoids within 3 months prior to ICI treatment 3. Lack of critical clinical data (e.g., lack of baseline data, inadequate follow-up time)

Design outcomes

Primary

MeasureTime frame
Immune-related adverse events;

Secondary

MeasureTime frame
Progression-free survival;

Countries

China

Contacts

Public ContactZhuqing Liu

Shanghai Tenth People's Hospital

liuzhuqing521@126.com+86 188 1787 9518

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026