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Development of a Predictive Machine Learning Model for Androgenetic Alopecia in Polycystic Ovary Syndrome: A Retrospective and Prospective Single-Center Study

Development of a Predictive Machine Learning Model for Androgenetic Alopecia in Polycystic Ovary Syndrome: A Retrospective and Prospective Single-Center Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109124
Enrollment
Unknown
Registered
2025-09-12
Start date
2025-09-30
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Androgenetic alopecia

Interventions

Polycystic Ovary Syndrome with Androgenetic Alopecia Group :None
Polycystic Ovary Syndrome without Androgenetic Alopecia Group :None

Sponsors

Beijing Friendship Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with PCOS according to the Rotterdam criteria at Beijing Friendship Hospital, Capital Medical University, i.e., those presenting any two of the following three features: (1) irregular menstrual cycles (cycle length >=45 days or =8 or serum total testosterone >=50 ng/dL); (3) polycystic ovarian morphology (ovarian volume >10 mL or>=12 follicles with a diameter of 2–9 mm); 2. Female patients aged 18 years or above who have not undergone menopause. 3. Availability of laboratory test results in the medical record system (including but not limited to endocrine six-item tests, which may cover anti-Müllerian hormone, biochemical C6, dehydroepiandrosterone sulfate, thyroid series, etc.), as well as reports from transabdominal/transvaginal ultrasound examinations, among others.

Exclusion criteria

Exclusion criteria: 1. Use of any relevant medications within 6 months prior to laboratory tests, such as oral contraceptives, insulin sensitizers, anti-androgen drugs, or Chinese herbal medicines; 2. Use of any relevant medications within 6 months prior to offline follow-up, such as oral contraceptives, insulin sensitizers, anti-androgen drugs, or Chinese herbal medicines; 3. Patients with other endocrine or organic disorders, such as hyperprolactinemia, thyroid dysfunction, Cushing's syndrome, congenital adrenal hyperplasia, adrenal or ovarian tumors, or impaired liver/kidney function; 4. Patients with severe traumatic injuries, infections, or severe systemic diseases; 5. Patients with oligomenorrhea due to other causes; 6. Pregnant or lactating women; 7. Individuals deemed ineligible by the investigator.

Design outcomes

Primary

MeasureTime frame
Ludwig scale for andrgenetic alopecia;

Secondary

MeasureTime frame
Basic demographic information;Laboratory parameters;Medical history and treatment history;

Countries

China

Contacts

Public ContactFenglin Zhuo

Beijing Friendship Hospital, Capital Medical University

zflsunny@hotmail.com+86 159 1089 5068

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026