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Study on the characteristics of oral microorganisms in the process of oral potentially malignant diseases

Characteristics of oral microbiota in the process of oral underlying malignant diseases

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109083
Enrollment
Unknown
Registered
2025-09-11
Start date
2023-07-31
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral potentially malignant diseases

Interventions

Control group:NA
Case group:NA

Sponsors

West China Hospital of Stomatology, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Case group: Age 18-70 years;Oral mucosal lesions such as oral lichen planus, oral leukoplakia, and other potentially malignant diseases of the oral cavity; 2.Control group: Age 18~70 years old;Oral mucosal lesions that are not known to be part of the OPMD, such as teeth that need to be extracted due to blocked teeth, supernumerary teeth, or orthodontic needs.

Exclusion criteria

Exclusion criteria: 1.Severe underlying systemic disease; 2.Use of prescription medications in the past 1 month that may affect the body's immunity and metabolism (e.g., glucocorticoids, immunosuppressants or enhancers, antifungals, probiotics, etc.); 3.Pregnant or breastfeeding women; 4.Presence of salivary gland disease affecting saliva production.

Design outcomes

Primary

MeasureTime frame
Shannon Index;—

Countries

China

Contacts

Public ContactZeng Xin

West China Hospital of Stomatology, Sichuan University

zengxin22@163.com+86 28 85503480

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026