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To explore the comparison between the advantages and disadvantages of rimazolam and etomid in the induction of laparoscopic surgery anesthesia

To explore the comparison between the advantages and disadvantages of rimazolam and etomid in the induction of laparoscopic surgery anesthesia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500109029
Enrollment
Unknown
Registered
2025-09-10
Start date
2025-09-20
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia induction outcomes

Interventions

Experimental group:Remimazolam anesthesia induction
Control group:Etomidate anesthesia induction

Sponsors

Qinzhou First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Age 20-50 years; 2. American Society of Anesthesiologists (ASA) physical status classification I-II; 3. Informed consent; 4. Voluntary participation in this trial.

Exclusion criteria

Exclusion criteria: 1. Presence of central nervous system diseases, long-term use of drugs that affect neuropsychiatric system functions such as hypnotics, anxiolytics, and antidepressants; 2. Cognitive dysfunction; 3. Severe dysfunction of heart, lung, liver, kidney, etc.; 4. Long history of smoking and alcohol abuse; 5. Severe visual or auditory impairments, communication barriers, inability to cooperate with the study, etc.; 6. Existence of underlying diseases such as hypertension, coronary heart disease, diabetes; 7. History of alcohol or drug abuse, use of painkillers before surgery; 8. Allergy to medications used in this study; 9. Need to maintain tracheal intubation after surgery; 10. Severe anemia before surgery or need for blood transfusion during surgery; 11. Presence of coagulation disorders; 12. Pregnancy or lactation; 13. Patients who experience severe complications during anesthesia.

Design outcomes

Primary

MeasureTime frame
Mean Arterial Pressure;Systolic Blood Pressure;Diastolic Blood Pressure;Heart Rate;Oxygen Saturation;

Secondary

MeasureTime frame
Surgical time;Anesthesia induction time;Recovery time;Postoperative hospital stay;Frequency of vasopressor use;

Countries

China

Contacts

Public ContactLizhu Lin

Qinzhou First People's Hospital

wyb4950lgr@163.com+86 189 0787 2800

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026