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Application of Infrared Spectroscopy in the Detection of Glucokinase Activity and Prediction of Individualized Therapeutic Efficacy of GKA

Application of Infrared Spectroscopy in the Detection of Glucokinase Activity and Prediction of Individualized Therapeutic Efficacy of GKA

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109017
Enrollment
Unknown
Registered
2025-09-10
Start date
2025-09-30
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

Observation Group:None

Sponsors

Zhejiang Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age 18 to 75 years; 2. Clearly diagnosed with type 2 diabetes according to the 'Chinese Diabetes Prevention and Treatment Guidelines (2024 Edition)', with HbA1c levels between 7.0% and 10.5%; 3. Meeting the treatment indications of the drug Metformin; 4. Signing the informed consent form to voluntarily participate in the study.

Exclusion criteria

Exclusion criteria: 1. Patients with severe heart failure (NYHA Class III-IV), liver dysfunction (ALT or AST exceeding 3 times the normal upper limit), and acute renal failure; 2. Those currently or recently suffering from acute infections, severe injuries, or recovery periods from surgeries that affect metabolic status; 3. Patients with concurrent malignant tumors or other serious diseases affecting prognosis and compliance; 4. Individuals using medications affecting glucose metabolism, such as systemic corticosteroids and immunosuppressants; 5. Pregnant or breastfeeding women, or those planning to become pregnant during the study; 6. Individuals with mental or neurological diseases affecting their judgment, or those unable to cooperate with follow-ups and sample collection.

Design outcomes

Primary

MeasureTime frame
Blood glucose;Hemoglobin A1c (HbA1c);Glycated Albumin (GA);Glucokinase activity;Infrared Spectroscopy Detection;

Secondary

MeasureTime frame
Liver Function;Renal Function;

Countries

China

Contacts

Public ContactDan Yu

Zhejiang Hospital

pepsiyu@foxmail.com+86 571 87377883

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026