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Observation of rituximab as initial treatment in patients with minimal change disease- a retrospective study

Observation of rituximab as initial treatment in patients with minimal change disease- a retrospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500109006
Enrollment
Unknown
Registered
2025-09-10
Start date
2025-09-15
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Minimal Change Disease

Interventions

Group of treatment with rituximab:None

Sponsors

Qilu Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1?Percutaneous renal biopsy was performed, and the pathological diagnosis was minimal change disease. 2?Pre-treatment biochemical levels met the diagnostic criteria for nephrotic syndrome: massive proteinuria (>3.5g/d), hypoalbuminemia (plasma albumin =6 months;

Exclusion criteria

Exclusion criteria: 1?Patients who did not undergo renal pathological examination or are not diagnosed with non-MCD; 2?Secondary renal diseases caused by various reasons, such as congenital or genetic disorders, early connective tissue diseases, infections, drug-induced nephropathy, etc. 3?Patients with severe comorbidities, such as malignancies. 4?Pregnant or breastfeeding women. 5?Patients with incomplete medical records or those lost to follow-up for various reasons.

Design outcomes

Primary

MeasureTime frame
Clinical curative effect;

Secondary

MeasureTime frame
Clinical curative effect;

Countries

China

Contacts

Public ContactYang Xiangdong

Qilu Hospital of Shandong University

yxd683@163.com+86 185 6008 3856

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026