Postpartum pain
Conditions
Interventions
Hydromorphone Group (H):Before removing the epidural catheter at the end of labor analgesia, 10 ml of sterile normal saline containing 0.5 mg of hydromorphone is injected into the epidural space.
Morphine group (M):Before removing the epidural catheter at the end of labor analgesia, 10 ml of sterile normal saline containing 1 mg of morphine is injected into the epidural space.
Blank:The epidural catheter should be removed immediately following the conclusion of labor analgesia.
Sponsors
Maternal and Child Health Hospital of Hubei Province
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 20-40 years who underwent epidural labor analgesia and voluntarily signed the consent form to participate in this trial; 2. American Society of Anesthesiologists (ASA) grade I.~II; 3.18.5<=BMI<=30; 4. No analgesic drug use within 3 months; 5. No mental disorders, intellectual disabilities and other diseases; 6. No history of drug abuse, drug abuse, or alcoholism; 7. Be able to communicate well and complete relevant questionnaires and questions.
Exclusion criteria
Exclusion criteria: 1. Patients and their families refuse to sign the informed consent form to participate in the trial; 2. ASA level III or above; 3. Previous history of allergy to narcotic drugs, allergy to the active ingredients and excipients of the drugs used; 4. Severe congenital heart disease or abnormal liver and kidney function (ALT<2ULN; SCr <1.5 times baseline, eGFR <25%); 5. Suffering from conscious disorders; 6. History of neurological diseases and mental illness; 7. There is a serious risk of increased blood pressure or intracranial pressure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual pain score;blood pressure;hreat rate;oxygen saturation;Edinburgh Postnatal Depression Scale (EPDS);Additional analgesic treatment;The perineal condition of the parturient; | — |
Secondary
| Measure | Time frame |
|---|---|
| degree of satisfaction;adverse event;Urination and defecation;Apagar score; | — |
Countries
China
Contacts
Public ContactQuan Yingyao
Maternal and Child Health Hospital of Hubei Province
Outcome results
None listed