Gastric retention
Conditions
Interventions
Healthy Volunteer Group A: Ingestion of 500 ml of water
Healthy Volunteer Group B:Ingestion of a 200 g hamburger
Healthy Volunteer Group C: Combined ingestion of 300 ml of water and a 200 g hamburger
Outpatient Group A:Administration of 20 ml of defoaming agent (simethicone emulsion)
Outpatient Group B:Administration of 40 ml of defoaming agent (simethicone emulsion)
Outpatient Group C:Administration of 60 ml of defoaming agent (simethicone emulsion)
Sponsors
Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Healthy volunteer queue Age 18 to 85 years; body weight 45 to 110 kg; height > = 145 cm; Fasting >= 8 hours, no water >= 2 hours; Able to understand the study procedures and sign the informed consent form. (2) Outpatient cohort Age 18 to 85 years; body weight 45 to 110 kg; height > = 145 cm; Fasting >= 8 hours, no water >= 2 hours; Patients who underwent gastroscopy in the gastroenterology department on the day of the experiment; Able to understand the study procedures and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Healthy Volunteer Cohort History of upper gastrointestinal bleeding within the past month; history of gastric surgery or known anatomical abnormalities of the upper gastrointestinal tract; use of medications affecting gastrointestinal motility (e.g., domperidone, mosapride) within the past month; inability to cooperate with ultrasound examination; pregnant and lactating women. (2) Outpatient Cohort History of upper gastrointestinal bleeding within the past month; history of gastric surgery or known anatomical abnormalities of the upper gastrointestinal tract; patients with upper gastrointestinal diseases (e.g., pyloric obstruction or stenosis, gastric tumors, gastric ulcers, severe gastrointestinal distension, diabetic gastroparesis); use of medications affecting gastrointestinal motility (e.g., domperidone, mosapride) within the past month; inability to cooperate with ultrasound examination; pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gastric ultrasound images; | — |
Countries
China
Contacts
Public ContactQian Lei Yue Liu
Sichuan Provincial People's Hospital
Outcome results
None listed