Chronic kidney disease
Conditions
Interventions
CKD patients:none
Patients with isolated hematuria and proteinuria:none
Health control:none
Patients with diabetes mellitus only:none
Sponsors
Southern Medical University Southern Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.CKD patients; 1.Voluntarily sign informed consent; 2.Age =18 years old; 3.Based on the patient's self-report, relevant laboratory tests, etc., it is determined that the patient is a CKD patient, with a clear CKD stage and the condition being in a stable state; 2.Patients with essential hypertension; 1.Age =18 years old; 2.Patients meeting the diagnostic criteria for hypertension without any other underlying diseases; 3.Patients with diabetes mellitus only; 1.Age =18 years old; 2.Patients meeting the diagnostic criteria for diabetes without any other underlying diseases; 4.Patients with isolated hematuria and proteinuria; 1.Age =18 years old; 2.Patients diagnosed with isolated hematuria and proteinuria with no other comorbidities; 5.Health control; 1.Voluntarily sign informed consent; 2.Age =18 years old; 3.A healthy control population from a physical check-up program with no known diseases and normal laboratory findings;
Exclusion criteria
Exclusion criteria: 1.CKD patients; 1.Acute kidney injury; patients undergoing dialysis or kidney transplantation; recent use of drugs that can affect creatinine levels; nephrotic syndrome; thyroid system diseases; severe edema or fluid balance disorders; severe heart, liver and lung dysfunction; infectious diseases; blood system diseases; malignant tumors at any site; pregnant women; lupus nephritis; 2.Samples with severe hemolysis and lipemia; 3.Poor image quality of the crystal; 4.According to the researchers' assessment, it was determined that they were not suitable to participate in this study; 2.Patients with essential hypertension; 1.eGFR<90 ml/(min×1.73m2); 2.Samples with severe hemolysis and lipemia; 3.Poor image quality of the crystal; 4.According to the researchers' assessment, it was determined that they were not suitable to participate in this study; 3.Patients with diabetes mellitus only; 1.eGFR<90 ml/(min×1.73m2); 2.Samples with severe hemolysis and lipemia; 3.Poor image quality of the crystal; 4.According to the researchers' assessment, it was determined that they were not suitable to participate in this study; 4.Patients with isolated hematuria and proteinuria; 1.Samples with severe hemolysis and lipemia; 2.Poor image quality of the crystal; 3.According to the researchers' assessment, it was determined that they were not suitable to participate in this study; 5.Health control; 1.Samples with severe hemolysis and lipemia; 2.Poor image quality of the crystal; 3.According to the researchers' assessment, it was determined that they were not suitable to participate in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity;Recall rate;Area under the Curve (AUC);F1 score;Specificity;Accuracy;Crystal morphology of uric acid; | — |
Countries
China
Contacts
Public ContactBo Situ
Southern Medical University Southern Hospital
Outcome results
None listed