Biliary atresia
Conditions
Interventions
High MCT nutrition group:High MCT Nutrition
Control group:Breast milk and regular complementary food
Sponsors
Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Children under 3 months old; 2. Clinically diagnosed children with biliary atresia who need to undergo Kasai surgery; 3.The patient himself/herself, the legal representative or the guardian should sign the informed consent form and actively cooperate with the treatment and follow-up.
Exclusion criteria
Exclusion criteria: 1. Low birth weight infants or very low birth weight infants; 2. Merging life-threatening diseases in various organ systems; 3. Other severe digestive tract malformations or other diseases that may interfere with the treatment of the child or the child's compliance; 4. Patients who have participated in other clinical trials within the last month; 5. Any other circumstances where the researcher deems it inappropriate to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The age-specific weight WAZ value 12 months after the operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nutritional indicators such as age-specific weight, height, BMI and Z-score were followed up 12 months after the operation;Nutritional indicators such as age-specific weight, height, BMI and Z-score were followed up 1 months after the operation;Three months after the operation, age-specific weight, height, BMI, Z-score and other nutritional indicators were followed up;Nutritional indicators such as age-specific height and BMI Z-score were followed up 6 months after the operation;Two years after the operation, age-specific nutritional indicators such as weight, height, BMI and Z-score were followed up;The jaundice regression rates at 1 month, 3 months, 6 months, 1 year and 2 years after the operation;The incidence rates of cholangitis at 1 month, 3 months, 6 months, 1 year and 2 years after the operation;The effective rate of Kasai surgery 6 months after the operation;Autologous liver survival rates at 1 month, 3 months, 6 months, 1 year and 2 years after the operation;Blood routine and blood biochemical indicators at 1 month, 3 months, 6 months, 1 year and 2 years after the operation;The content of fat-soluble vitamins at 1 month, 3 months, 6 months, 1 year and 2 years after the operation;Total length of hospital stay;Readmission rates at 1 month, 3 months, 6 months, 1 year and 2 years after the operation; | — |
Countries
China
Contacts
Public ContactTianqi Zhu
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed