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Development and validation of a prognostic risk prediction model for patients with type A aortic dissection based on the ACEF score

Development and validation of a prognostic risk prediction model for patients with type A aortic dissection based on the ACEF score

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500108961
Enrollment
Unknown
Registered
2025-09-09
Start date
2025-09-09
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Dissection

Interventions

Training set:No.
Test set:No.

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years; 2. Acute type A aortic dissection (TAAD) confirmed by computed tomography angiography (CTA) or intra-operative findings; 3. Emergency surgical repair performed within 14 days of symptom onset; 4.Complete peri-operative and follow-up clinical data available.

Exclusion criteria

Exclusion criteria: 1. Age 14 days); 3. Isolated intramural hematoma (IMH), penetrating aortic ulcer (PAU), or aortic aneurysm without dissection; 4. Previous aortic surgery or stent graft placement; 5. Concomitant severe congenital heart disease, infective endocarditis, or concomitant cardiac procedures (e.g., CABG, valve replacement); 6. Malignancy or end-stage organ disease with life expectancy < 1 year; 7. Pregnancy; 8. Major missing clinical or follow-up data.

Design outcomes

Primary

MeasureTime frame
Adverse Prognostic Outcomes (APO);Aortic-Related Adverse Outcomes (ARAO);

Secondary

MeasureTime frame
In-hospital mortality;Length of ICU stay;Duration of mechanical ventilation;Incidence of AKI;Low cardiac output syndrome;Stroke;Re-thoracotomy for bleeding;Overall survival (OS);ARAO-free survival;All-cause mortality during follow-up;

Countries

China

Contacts

Public ContactLinfeng Xie

Fujian Medical University Union Hospital

lysxxlf@vip.qq.com+86 152 8019 1181

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026