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Comparison of the efficacy and safety of laryngeal surface anesthesia and superior laryngeal nerve block in microscopically supported laryngoscopy surgery, a randomized double-blind controlled trial

Comparison of the efficacy and safety of laryngeal surface anesthesia and superior laryngeal nerve block in microscopically supported laryngoscopy surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108953
Enrollment
Unknown
Registered
2025-09-09
Start date
2025-09-15
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vocal cord diseases

Interventions

Pharyngeal surface anesthesia group:Spray 5ml of 2% lidocaine under the glottis of the throat
Ultrasound-guided bilateral superior laryngeal nerve block group:Ultrasound-guided bilateral superior laryngeal nerve block with 1% lidocaine, 3ml on each side

Sponsors

Anqing Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Patients who are scheduled to undergo microscopic-supported laryngoscopy surgery; 2.ASA classification I-III; 3.The patient's age is >=18 years old and <=65 years old. 4.BMI index: 18-28 kg/m ^2; 5.Ethical compliance, patients voluntarily accepted this trial and signed the informed consent form

Exclusion criteria

Exclusion criteria: 1.Severe dysfunction of the heart, lungs, liver and kidneys; 2.Have a history of mental illness or long-term psychotropic drugs (dementia, schizophrenia); 3.Allergy to lidocaine or contraindications for superior laryngeal nerve puncture; 4.Those who have language communication impairments, hearing impairments or brain function disorders such as stroke and are unable to communicate; 5.Those who are not suitable for endotracheal general anesthesia as assessed before the operation; 6.Participated in other drug clinical studies within the past 30 days.

Design outcomes

Primary

MeasureTime frame
The blood pressure and heart rate of the patient at the time of entering the room, after anesthesia induction, immediately after tracheal intubation, when the laryngoscope is placed, after polyp removal, when the tracheal tube is extugated, and when leaving the PACU;

Secondary

MeasureTime frame
General patient information (age, gender, ASA classification and comorbidities, etc.);The incidence of choking cough during extubation;Time:Operation time, anesthesia time, PACU retention;The dosage of vasoactive drugs and anesthetic drugs;Incidence of postoperative complications (pharyngeal pain, dysphagia, respiratory depression, laryngeal spasm, restlessness during the recovery period, nausea and vomiting);Hospital stay;Patient satisfaction with anesthesia;

Countries

China

Contacts

Public ContactXu Huang

Anqing Municipal Hospital

393864473@qq.com+86 158 5657 5382

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026