Post-traumatic stress disorder
Conditions
Interventions
The dexmedetomidine group:Inhalation of dexmedetomidine+normal saline sham block
Stellate Ganglion Block Group:Stellate ganglion block+nasal spray of normal saline
The dexmedetomidine + stellate ganglion block group:Inhalation of dexmedetomidine + stellate ganglion block
Nasal spray of normal saline + normal saline sham block group:Nasal spray of normal saline+normal saline sham block
Sponsors
Baoding First Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age 18 or older; 2.The plan is to undergo an emergency surgery under general anesthesia; 3.American Society of Anesthesiologists (ASA) physical status I-III E; 4.Obtained the consent of the patients and their families, and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1.A known allergy to dexmedetomidine or ropivacaine; 2.Severe liver and kidney dysfunction; 3.Skin infection at the puncture site; 4.Combine severe neurological or mental disorders unable to undergo assessmtent; 5.Craniocerebral or spinal cord injury; 6.Uncorrected hemorrhagic shock; 7.Associated with multiple and complex injuries and requiring concurrent implementation of multiple surgical procedures; 8.Severe atrioventricular block or bradyarrhythmia with a baseline heart rate lower than 50 beats/min; 9.Severe visual, hearing, or speech impairments that prevent the completion of assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence rate of post-traumatic stress disorder; | — |
Secondary
| Measure | Time frame |
|---|---|
| the severity of post-traumatic stress disorder;Delayed PTSD;Intrusion Symptoms;Avoidance Symptoms;Negative Alterations in Cognitions and Mood;Alterations in Arousal and Reactivity;The Beck Anxiety Inventory scores;Visual Analogue Scale (VAS) postoperative pain scores;Numerical Rating Scale (NRS) sleep score;Heart Rate Variability;Quality of Recovery-15 scores;Length of hospital stay;Surgical satisfaction;Patient satisfaction; | — |
Countries
China
Contacts
Public ContactZhu Lei
Baoding First Central Hospital
Outcome results
None listed