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Comparative study of perfluorobutane microsphere contrast-enhanced ultrasound and enhanced CT in evaluating preoperative N staging of gastric cancer

Comparative study of perfluorobutane microsphere contrast-enhanced ultrasound and enhanced CT in evaluating preoperative N staging of gastric cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108940
Enrollment
Unknown
Registered
2025-09-09
Start date
2025-09-09
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Experimental group:All research participants underwent enhanced CT and perfluorobutane microbubble ultrasound imaging.

Sponsors

Shandong First Medical University First Affiliated Hospital (Shandong Qianfoshan Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Able to understand and voluntarily sign a written informed consent form, which must be signed before the designated research procedures required for the study are performed. Able to understand and voluntarily sign a written informed consent form, which must be signed before the designated research procedures required for the study are performed. 2. Aged >= 18 years and = 6 months. 7. Able to cooperate with the implementation of this protocol.

Exclusion criteria

Exclusion criteria: 1. Evidence of distant organ metastasis exists. 2. There is clinically symptomatic cancerous pleural effusion, pericardial effusion, or ascites requiring frequent drainage. 3. A history of other malignant tumors. 4. Poor nutritional status, BMI 2), such as severe pneumonia, bacteremia, and infectious complications requiring hospitalization; active pulmonary inflammation based on baseline chest X-ray; infections requiring oral or IV antibiotic treatment occurring within 14 days prior to the first dose (excluding prophylactic antibiotic use). 8. Patients with a history of active tuberculosis infection or CT imaging showing active tuberculosis; or patients with a history of active tuberculosis infection within the past year; or patients with active tuberculosis infection who have not received systemic treatment for over a year. 9. The presence of active hepatitis B (HBV DNA >= 2000 IU/mL or 10^4 copies/mL) or hepatitis C (positive for hepatitis C antibody, HCV RNA above detection limit). 10. Known active syphilis infection. 11. Women who are pregnant or breastfeeding. 12. Currently participating in another clinical study, as well as other factors judged by the investigator that may lead to the participant being forced to withdraw from the study, such as other severe diseases needing simultaneous treatment (including mental health issues), alcohol abuse, drug misuse, and family or social factors that may affect the safety or compliance of the study participants.

Design outcomes

Primary

MeasureTime frame
Enhanced CT and perfluorobutane microbubble ultrasound imaging improve the accuracy of N staging diagnosis.;

Secondary

MeasureTime frame
Perfluorobutane microsphere lymph node imaging time;

Countries

China

Contacts

Public ContactZhang Guangyong

Shandong First Medical University First Affiliated Hospital (Shandong Qianfoshan Hospital)

gyzhang3369@sdfmu.edu.cn+86 158 0664 3369

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026