Urethral stricture
Conditions
Sponsors
Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Male patients scheduled for a urethral surgery under general anesthesia; 2. Age ranging from 18 to 65 years old; 3. ASA classification grade I to III; 4. BMI ranging from 18 to 30 kg/m^2; 5. Voluntary use of postoperative intravenous analgesic pump; 6. Patients or authorized family members have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. There are contraindications for using oliceridine (such as severe respiratory depression, paralytic intestinal obstruction, and allergy to oliceridine); 2. The surgical site was painful before the operation; 3. Long-term use of psychotropic drugs or opioid drugs; 4. Severe impairment of heart, lung, liver, and kidney functions; 5. Allergic to other drugs involved in this study; 6. Difficult cooperation, intellectual disability, or cognitive dysfunction before the operation; 7. Has participated in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative nausea and vomiting;Postoperative respiratory depression;Postoperative drowsiness;Sleep disturbance;The time of the first rescue analgesia after surgery and the number of rescue analgesia administrations;The time of the first postoperative ambulation;EuroQol Five-Dimensional Scale Score;inflammatory factor;Anxiety and depression scores;postoperative moderate to severe acute pain;Blood test indicators;Additional adverse reactions; | — |
Countries
China
Contacts
Public ContactYushan Dong
Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Outcome results
None listed