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Effects of different puncture locations (S2vS3) on endoscopic ultrasound-guided anterograde biliary therapy: a prospective multicenter randomized controlled study

Effects of different puncture locations (S2vS3) on endoscopic ultrasound-guided anterograde biliary therapy: a prospective multicenter randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108923
Enrollment
Unknown
Registered
2025-09-09
Start date
2025-09-30
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biliary obstruction

Interventions

Group S2:Puncture was performed using segment II of the liver
Group S3:Puncture was performed using segment III of the liver

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. 18-80 years old; 2. The initial ERCP failed; 3. There is jaundice or abnormal liver function; 4.EUS and/or CT and/or MRI revealed intrahepatic bile duct dilation; 5. The histopathological diagnosis of malignant tumors or the combined follow-up of imaging for 6 months tended to diagnose malignant tumors, and the unresectability of potential malignant tumors was determined through MDT consultation (the obstruction site was located at the distal hilum of the liver > 2cm); 6. The stone is less than 1.5cm; 7. Agree to participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.In patients with coagulation dysfunction (INR>1.3), the peripheral blood microplate count was significantly reduced to <50 ×10^9/L; 2. Pregnant women; 3. High biliary obstruction; 4. The stone is larger than 1.5cm; 5. Refuse to participate in this study and refuse to sign the informed consent form; 6. Other contraindications for endoscopic interventional therapy;

Design outcomes

Primary

MeasureTime frame
The success rate of anteroposterior biliary tract treatment techniques;The clinical success rate of anteroposterior biliary tract treatment technology;

Secondary

MeasureTime frame
Operation time;

Countries

China

Contacts

Public ContactHou Senlin

The Second Hospital of Hebei Medical University

housenlin@hebmu.edu.cn+86 158 0321 9882

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026