Postpartum Blues
Conditions
Interventions
Experimental : Active taVNS Group:Participants receive active stimulation of the left cymba conchae at a frequency of 25 Hz and pulse width of 300 µs, delivered in alternating 30-second on / 30-second
Sham Comparator : Sham taVNS Group:Participants undergo identical procedures to the active group, with electrodes placed on the left cymba conchae. After determining the maximum tolerated intensity, s
Sponsors
Huzhou Maternity & Child Health Care Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18 and 45 years; 2. Pre-pregnancy body mass index (BMI) of 18.5–40 kg/m^2; 3. Medically healthy with stable cardiovascular vital signs; 4.American Society of Anesthesiologists (ASA) physical status I–III; 5. Scheduled for elective cesarean section at Huzhou Maternal and Child Health Hospital; 6. Capable of understanding study procedures and assessment instruments, and able to communicate effectively with research personnel; 7. Provides voluntary informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1. History of psychiatric disorders; 2. Prior diagnosis of depression; 3. Severe cardiovascular or cerebrovascular conditions; 4. Thyroid dysfunction or endocrine disorders affecting mood; 5. Current use of medications that influence mood or treat conditions associated with mood instability; 6. Disorders of reproductive hormone metabolism or recent hormonal therapy; 7. Presence of significant preoperative depression risk factors (e.g., prolonged exposure to domestic violence, recent bereavement); 8. Current or past history of smoking.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in depressive mood(the severity of PPB); | — |
Secondary
| Measure | Time frame |
|---|---|
| Profile of Mood States (POMS);Stein Maternity Blues Scale;Postpartum Depression;Postoperative Pain;Postoperative Sleep Quality; | — |
Countries
China
Contacts
Public ContactQin Cheng
Huzhou Maternity & Child Health Care Hospital
Outcome results
None listed