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The application of Yesucom chitosan eye moisturizer in adult soft contact lens wearers

The application of Yesucom chitosan eye moisturizer in adult soft contact lens wearers

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108863
Enrollment
Unknown
Registered
2025-09-08
Start date
2025-09-08
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Soft lens nursing

Interventions

Study PARTICIPANTS:Patients were required to wear the assigned model of daily application contact lenses for at least 8 hours per day, at least 5 days per week. Use the same eye moisturizer for both e
2) At noon, drop eye moisturizer into the conjunctival sac while wearing glasses
3) Drop eye moisturizer into the conjunctival sac after removing the glasses. After using one eye moisturizer for two weeks, replace the other eye moisturizer with the same way of eye drops Daily eye
Control group:Patients were required to wear the assigned model of daily application contact lenses for at least 8 hours per day, at least 5 days per week. Use the same eye moisturizer for both eyes 3

Sponsors

Eye & ENT Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) At the time of enrollment, 18 years old to 60 years old, regardless of gender; 2) not wearing contact lenses in the past 3 days; 3) no history of corneal refractive surgery in both eyes; 4) no use of dry eye medication within 7 days before enrollment 5) able to understand the purpose of the trial, voluntarily participate in the trial, sign the informed consent form by the patients themselves, and be able to complete the follow-up on time; 6) if the study participant is female, not pregnant and not planning a recent pregnancy.

Exclusion criteria

Exclusion criteria: 1) The range of corneal damage was more than 2 quadrants by slit-lamp examination, and (or) the number of corneal fluorescein staining points was more than 30, and TBUT was less than 2s. Severe dry eye was diagnosed when the corneal fluorescein staining spots fused to thick spots, sheets, or with filamentous matter. 2) any infectious or non-infectious eye diseases such as corneal ulcer, conjunctivitis, scleritis, uveitis; 3) any ocular trauma, ocular tumor, glaucoma, cataract, fundus disease and other ocular diseases that need further treatment; 4) with severe or unstable heart, liver, kidney, lung, endocrine (including thyroid insufficiency, diabetes, etc.), autoimmune diseases (including Sjogren's syndrome, etc.), blood, mental and neurological disorders, etc. 5) pregnant and lactating women; 6) current use or planned use during the study of medications that may cause dry eye; 7) other conditions judged by the investigator that the patient was not suitable for inclusion;

Design outcomes

Primary

MeasureTime frame
Fluorescein Breakup Time,FBUT;Slit-lamp examination;Corneal fluorescein staining,CFS;The anterior segment was photographed after corneal fluorescein staining;Tear river height;Questionnaire survey;

Secondary

MeasureTime frame
Lens protein residue detection;

Countries

China

Contacts

Public ContactCHEN ZHI

Eye & ENT Hospital of Fudan University

peter459@aliyun.com+86 136 0420 2085

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026