Acquired Immune Deficiency Syndrome
Conditions
Interventions
HIV Non-Oral Lesion Group:N/A
AIDS Oral Lesion Group:N/A
Healthy Control Group:N/A
Sponsors
Beijing Youan Hospital, Capital Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.HIV Non-Oral Lesion Group:(1) Age 18 years or older;(2) No lesions or damage to the oral mucosa;(3) Patients who are HIV antibody positive. 2.AIDS Oral Lesion Group:(1) Meet the diagnostic criteria for AIDS;(2) Age 18 years or older;(3) Presence of oral lesions: patients with non-Hodgkin lymphoma. 3.Healthy Control Group:(1) Age 18 years or older;(2) No lesions or damage to the oral mucosa;(3) Patients who are HIV antibody negative.
Exclusion criteria
Exclusion criteria: 1.HIV Non-Oral Lesion Group:(1) Pregnant or breastfeeding women;(2) Individuals with lesions or damage to the oral mucosa;(3) Use of oral or topical antibiotics, glucocorticoids, or immunomodulatory drugs within 3 months prior to examination;(4) Individuals who did not sign the informed consent form. 2.AIDS Oral Lesion Group:(1) Individuals with non-HIV-related oral infections or oral tumor diseases;(2) Patients with psychiatric disorders;(3) Individuals with a history of drug abuse;(4) Pregnant or breastfeeding women;(5) Individuals who did not sign the informed consent form. 3.Healthy Control Group:(1) Pregnant or breastfeeding women;(2) Individuals with lesions or damage to the oral mucosa;(3) Use of oral or topical antibiotics, glucocorticoids, or immunomodulatory drugs within 3 months prior to examination;(4) Individuals who did not sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Th17 cell count in whole blood;IL-17 concentration in saliva supernatant; | — |
Countries
China
Contacts
Public ContactYing Guo
Beijing Youan Hospital, Capital Medical University
Outcome results
None listed