Prostatic hyperplasia
Conditions
Interventions
Experimental group:Oliceridine is used for perioperative analgesia.
Control group:Sufentanil for perioperative analgesia
Sponsors
Renjin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
Male
Age
70 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age: 70 years old <= age <= 90 years old; 2. Patients who are planned to undergo transurethral laser enucleation of the prostate under general anesthesia; 3. Patients participate voluntarily and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Previous severe cerebrovascular accidents and other neurological disorders: such as neuroimmune diseases, central nervous system infections, movement disorders (such as Parkinson's disease, etc.), hereditary neurological diseases, developmental abnormal diseases, etc; 2. Mental disorders, long-term use of drugs affecting the function of the central nervous system, benzodiazepines or opioids; 3. History of allergy to anesthetic drugs; 4. Preoperative hypotension or preoperative SpO2 = 6 standard drinks/day); 7. Patients diagnosed with severe cardiopulmonary diseases, or respiratory system diseases or respiratory tract diseases: such as sleep apnea syndrome; 8. Bradycardia or atrioventricular block; 9. Participation in other clinical trials within 4 weeks; 10. Abnormal cognition or communication as determined by the researcher; 11. Emergent critical situations during the operation; 12. Other conditions deemed unsuitable for participation in the study by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of laryngeal mask removal; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events during the perioperative period/PACU;The patient's hemodynamic status;Time to recovery of spontaneous breathing;Duration of stay in the Post-Anesthesia Care Unit (PACU);The incidence of postoperative hypoxia;Patient satisfaction with anesthesia and postoperative recovery/NRS score;The incidence of other adverse events during and after the operation;NRS scores at 6, 9 and 24 hours after leaving the PACU; | — |
Countries
China
Contacts
Public ContactHui Zhu
Renjin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Outcome results
None listed