Depression
Conditions
Interventions
Intervention group:Interoceptive Respiratory Attention Training task, followed by two interventions per day, 15 minutes each, with an interval of >= 4 hours between the two sessions, for a total of 10
Control group:Neutral Audio Intervention Task, followed by two interventions per day, 15 minutes each, with an interval of >= 4 hours between the two sessions, for a total of 10 sessions.
Sponsors
Shandong Daizhuang Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Meeting the diagnostic criteria for major depressive disorder as assessed by the Structured Clinical Interview for DSM-5 (SCID-V); 2. Aged between 18 and 60 years; 3. Right-handed; 4. Capable of understanding and complying with the study protocol.
Exclusion criteria
Exclusion criteria: 1. History of substance dependence (including alcohol or drug dependence); 2. Presence or history of other psychiatric disorders meeting diagnostic criteria on SCID Axis I; 3. Current or previous traumatic brain injury or other known organic central nervous system impairments; 4. Systematic physical therapy received within the past six months (e.g., electroconvulsive therapy, transcranial magnetic stimulation); 5. Personal or family history of epilepsy, or a positive family history of psychiatric disorders in first- or second-degree relatives; 6. Pregnancy or lactation; 7. Previous experience with mindfulness or meditation practices.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ameliorative effects of interoceptive respiratory attention training on depressive symptoms (HAMD-24), anhedonia (SHAPS), and emotion regulation (DERS) in patients with depression.;The predictive effect of acute neuroelectrophysiological changes (resting-state and task-state) induced by interoceptive respiratory attention training on symptom improvement in patients with depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| The improving effects of interoceptive respiratory attention training on resting-state and task-state neuroelectrophysiological indicators in patients with depression;The optimizing effects of interoceptive respiratory attention training on behavioral measures of reward processing and emotion regulation in patients with depression;The individualized changes in neuroelectrophysiological (resting-state/task-state), behavioral (reward processing/emotion regulation), and clinical symptom measures (depressive symptoms (HAMD-24), anhedonia (SHAPS), emotion regulation (DERS)) among depression patients with different levels of interoceptive awareness following interoceptive respiratory attention training;The ameliorative effects of interoceptive respiratory attention training on self-rated depression (SDS), self-rated anxiety (SAS), anxiety symptoms (HAMA), and functional status in work, social, and family life (SDS) among patients with depression; | — |
Countries
China
Contacts
Public ContactLi Kun
Shandong Daizhuang Hospital
Outcome results
None listed