Gastritis
Conditions
Interventions
propofol combined with lidocaine:dose of propofol: 0.6 mg/kg
ciprofol combined with lidocaine:Intravenous injection of ciprofol at the ED95 dose determined in a previous study.
Sponsors
The Second Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
7 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1.Age range: 7 to 12 years. 2.Body mass index (BMI) ranges: 14.0-19.3 kg/m^2 for ages 5-7 years, 14.7-20.4 kg/m^2 for ages 8-10 years, and 15.4-22.4 kg/m^2 for ages 11-12 years. 3.American Society of Anesthesiologists (ASA) physical status classification I-II. 4.Normal developmental status. 5.Informed consent was obtained from the legal guardians of the children prior to anesthesia.
Exclusion criteria
Exclusion criteria: 1.Allergy to ciprofol or propofol or lidocaine. 2.Confirmed difficult airway. 3.Ongoing sedative therapy (e.g., propofol, morphine, fentanyl, sufentanil, midazolam, dexmedetomidine, ketamine) or recent use of sedatives (withdrawal time <24 hours). 4.Cardiac or respiratory diseases. 5.Hepatic or renal dysfunction. 6.Developmental malformations or delays. 7.If any of the above answers is "No," the subject is excluded from participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation success rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic Blood Pressure (SBP);Diastolic Blood Pressure (DBP);Heart Rate (HR);Oxygen saturation;Incidence of adverse effects;Onset Time of Sedation;rescue sedative administration;emergence time; | — |
Countries
China
Contacts
Public ContactRuifeng Zeng
Department of Anesthesiology, The 2nd Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed