Postoperative pain
Conditions
Interventions
Intervention Group:Ultrasound-Guided Quadratus Lumborum Block (QLB) + Diclofenac Sodium Suppository
Control Group:Sufentanil + Parecoxib Sodium
Sponsors
Hanzhong Central Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Nulliparous women (women undergoing their first pregnancy and childbirth) scheduled for elective cesarean section under single-shot spinal anesthesia; 2. Aged 18 to 35 years; 3. American Society of Anesthesiologists (ASA) physical status classification I-II; 4. No underlying diseases, including hypertension, diabetes mellitus, and heart disease; 5. Term pregnant women (with a gestational age of 37 to 42 weeks); 6. Informed consent signed by the patient herself or her immediate family members on her behalf.
Exclusion criteria
Exclusion criteria: 1. Local or systemic infection: Skin infection at the block site, systemic infectious diseases, or sepsis; 2. Coagulation disorders: Abnormal coagulation function, such as prolonged prothrombin time (PT) and activated partial thromboplastin time (APTT), platelet count < 100×10?/L, or other coagulation impairments; 3. Severe spinal or lumbar diseases: Conditions that affect puncture operation or increase the risk of nerve injury, such as spinal deformity, acute episode of lumbar disc herniation, spinal stenosis, and abnormal anatomical structure of the quadratus lumborum muscle; 4. Allergy to anesthetic drugs: Known allergy to local anesthetics (e.g., lidocaine, ropivacaine, etc.) or intravenous analgesic drugs (e.g., sufentanil); 5. Pregnancy complicated with severe complications: Conditions requiring emergency cesarean section or affecting the anesthesia plan, such as severe preeclampsia and placental abruption; 6. Other contraindications: Cardiac insufficiency (without underlying heart disease but with perinatal cardiac dysfunction), severe hepatic or renal insufficiency, etc; 7. Administration of sedatives, antiemetics, anti-motion sickness drugs, or anti-pruritic drugs within 48 hours before surgery; 8. Emergency cesarean section; 9. Cesarean section with vertical incision.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS scores at different time after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ramsay Sedation Scale;Total Presses of PCIA,Effective Presses of PCIA,Actual Drug Consumption of PCIA;Time to First Ambulation After Surgery,Time to Bowel Function Recovery After Surgery;Drug Costs,Hospitalization Expenses,Additional Medical Costs Due to Complications;Neonatal Sedation Assessment Scales;Maternal Sleep Quality Assessment Scales;Maternal Satisfaction Score for Analgesic Efficacy; | — |
Countries
China
Contacts
Public ContactHuang Heng
Hanzhong Central Hospital
Outcome results
None listed