Wet age-related macular degeneration
Conditions
Interventions
Injection Zhuo Chuming observation group:None
Inject the Arya observation group:None
Sponsors
Shandong Provincial Hospital Affiliated to Shandong First Medical University
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age>=50 years old; 2. Patients with nAMD diagnosed by fluorescein fundus angiography and/or indocyanine green angiography, OCT, and OCTA; 3. Patients who have been treated with other anti-VEGF drugs before enrollment and are referred to refractory nAMD, and can be treated on time and followed up for more than 24 weeks; 4. Good general condition, no serious cardiovascular and cerebrovascular diseases. 5. Patients need to have the ability to understand the content, purpose, process, risks and benefits of the study and voluntarily sign the informed consent form (signed by a legal representative for those who are incapacitated), and their economic status and social support need to be evaluated to ensure the feasibility of participation.
Exclusion criteria
Exclusion criteria: 1. High myopia correlation CNV; 2. Polypoid choroidal vascular lesion; 3. CNV secondary to central serous chorioretinopathy; 4. Retinal vascular or inflammatory diseases combined with CNV; 5. Severe opacity of the refractive stroma interferes with OCTA imaging 6. History of internal eye surgery or photodynamic therapy treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retinal thickness;Oroidal thickness;Vision; | — |
Secondary
| Measure | Time frame |
|---|---|
| Choroidal vascular condition;The number of intravitreal drug injections during the follow-up period;Fundus bleeding;Exudate; | — |
Countries
China
Contacts
Public ContactWeiyan Zhou
Shandong Provincial Hospital Affiliated to Shandong First Medical University
Outcome results
None listed