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Efficacy Analysis and Evaluation of Repeated Intravesical Injection of Platelet-Rich Plasma in the Treatment of Interstitial Cystitis/Bladder Pain Syndrome

Efficacy Analysis and Evaluation of Repeated Intravesical Injection of Platelet-Rich Plasma in the Treatment of Interstitial Cystitis/Bladder Pain Syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500108737
Enrollment
Unknown
Registered
2025-09-04
Start date
2025-09-04
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary bladder pain syndrome

Interventions

Experimental group:PRP two-stage intravesical injection (first once a week three times a week, then once a month three times a month) with 15 ml each time. (PRP extraction method is chosen by the pati

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. 18 years old< = age< = 80 years old; 2. Typical glomerular hemorrhage-like changes after cystoscopic water dilatation; 3. Preoperative examination to rule out other diseases such as tumors; 4. Have received at least 2 or more traditional treatment methods recommended by guidelines including oral drugs and bladder perfusion in the past, but the symptoms have not improved or recurred; 5. All patients voluntarily participated in this study and signed the relevant informed consent form.

Exclusion criteria

Exclusion criteria: 1. Hemoglobin (Hb) < 120 g/L, platelet (Plt) < 120×10^9/L; 2. Recurrent urinary tract infections or recent acute urinary tract infections; 3. Severe liver and kidney dysfunction or cardiac insufficiency who cannot tolerate intravenous general anesthesia; 4. Women who plan to become pregnant, pregnant or lactating; 5. Patients with ulcerative symptoms of cystoscopy; 6. Other situations that the investigator considers unsuitable for participation in the study

Design outcomes

Primary

MeasureTime frame
General reaction assessment;

Secondary

MeasureTime frame
Urinary diary;O'leary-sant score;Pain visual analogue scale score,VAS;Pelvic pain and urgency,frequency score,PUF;

Countries

China

Contacts

Public ContactWang Qingwei

The First Affiliated Hospital of Zhengzhou University

wangwang4677@126.com+86 371 6796 7232

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026