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A Retrospective Study on Real-World Treatment Regimens for dMMR/MSI-H Rectal Cancer

A Retrospective Study on Real-World Treatment Regimens for dMMR/MSI-H Rectal Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500108712
Enrollment
Unknown
Registered
2025-09-03
Start date
2025-09-03
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rectal cancer

Interventions

experimental group 1:neoadjuvat immunotherapy (NO ACTUAL INTERVENTION)
experimental group 2:neoadjuvat chemoradiotherapy (NO ACTUAL INTERVENTION)
control group:no neoadjuvant therapy (NO ACTUAL INTERVENTION)

Sponsors

Sun Yat-Sen University Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 99 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria were: patients with pathologically confirmed dMMR/MSI-H rectal cancer who received treatment at our hospital between January 1, 2011, and December 31, 2020.

Exclusion criteria

Exclusion criteria: Exclusion criteria were: 1) patients with prior treatment history; 2) patients with unknown clinical staging.

Design outcomes

Primary

MeasureTime frame
Progression Disease;Tumor Regression Grade;Death;Overall survival, OS;Disease-free Survival, DFS;—

Countries

China

Contacts

Public ContactZhang Rongxin

Sun Yat-Sen University Cancer Center

zhangrx@sysucc.org.cn+86 139 2617 5277

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026