Breast cancer
Conditions
Interventions
C Group:Sham press needles were implemented 30 minutes before anesthesia induction, and an equivalent volume of normal saline was initiated before anesthesia induction and continuously infused intraop
L Group:Sham press needles were applied 30 minutes before anesthesia induction. While 1% lidocaine (1.5 mg/kg) was intravenously infused over 10 minutes starting 10 minutes before anesthesia induction
NL Group:Press-needle therapy was administered 30 minutes before anesthesia induction, and 1% lidocaine (1.5 mg/kg) was intravenously infused over 10 minutes starting 10 minutes before anesthesia indu
Sponsors
Jiangsu Cancer Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: (1) Patients scheduled for unilateral radical mastectomy with ipsilateral sentinel lymph node biopsy (SLNB) or modified radical mastectomy for breast cancer; (2) ASA physical status classification I-II; (3) Age 18-64 years; (4) BMI 18.5-27.9 kg/m²; (5) Patient or family member has provided signed informed consent.
Exclusion criteria
Exclusion criteria: (1) History of allergy to Lidocaine, Opioids, Alcohol, or Adhesive tape; (2) History of analgesic medication use within the past month; (3) Preoperative history of chronic pain in the surgical area; (4) Preoperative severe systemic diseases (e.g., cardiac, pulmonary, hepatic, renal); (5) Received acupuncture or electroacupuncture therapy within the past two weeks; (6) Infection at acupoint sites.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total remifentanil dosage ;Postoperative NRS scores;Postoperative adverse reactions; | — |
Secondary
| Measure | Time frame |
|---|---|
| 15-item Recovery Quality Scale;Neutrophil count;Lymphocyte count;The ratio of neutrophils to lymphocytes;Platelet-to-lymphocyte ratio;Vascular endothelial growth factor-A;Matrix metalloproteinase;Interleukin-6;Interleukin-10;Interleukin-17;The incidence of chronic pain 3 months after the operation; | — |
Countries
China
Contacts
Public ContactQingming Bian
The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research
Outcome results
None listed