Sleep Quality and Anesthesia
Conditions
Interventions
Mild sleep apnea-hypopnea syndrome group:None
Severe sleep apnea-hypopnea syndrome:None
Sponsors
Children's Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
5 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Age: 5 to 12 years old, no gender restrictions; 2. ASA anesthesia classification I to II; 3. Elective tonsillectomy and adenoidectomy; 4. Preoperative sleep apnea screening; 5. Estimated anesthesia and surgery duration <=120 minutes; 6. Informed consent signed by the child's parent or legal guardian.
Exclusion criteria
Exclusion criteria: 1. Body mass index (BMI): BMI >=28kg/m^2 or upper limit of normal reference value); hepatic impairment (ALT and/or AST > 1.5 times upper limit of normal reference value); 8. Children with a history of severe head trauma or intracranial hypertension within 6 months; 9. History of preterm labor or intrauterine growth retardation; 10. Children with chronic neurological or psychiatric disorders (e.g., autism, Tourette's syndrome, epilepsy, etc.) or inability to express their wishes correctly; 11. Children with a history of chronic sedative-analgesic medications or monoamine oxidase inhibitors; 12. Children with an expected blood loss of more than 100 ml during surgery; 13. Children with other conditions that, in the opinion of the investigator, make them unsuitable for enrollment, such as coagulation abnormalities or genetic abnormalities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bispectral index;Anesthetic dosage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality;Blood pressure;Heart rate;Extubation time;Duration of surgery;Awakening Time;Sleep habits;Level of anxiety;Agitation-Sedation Scale;Pain Score;Pulse Oxygen Saturation; | — |
Countries
China
Contacts
Public ContactLiu Tingting
Children's Hospital of Zhejiang University School of Medicin
Outcome results
None listed