Gastric cancer
Conditions
Interventions
Observation group:None
Sponsors
Department of General Surgery, Zhongshan Hospital, Fudan University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Voluntarily sign the informed consent form; 2. Age greater than or equal to 18 years old and less than 80 years old; 3. Serum specimens can be collected before surgery, and the quality of the specimens meets the requirements of glycomics analysis. 4. Highly suspected EGC by endoscopic biopsy or imaging evaluation, that is, tumor invasion is limited to the mucosa or submucosa; and subjects who are diagnosed with EGC by surgical specimen within 30 days after blood collection; 5. Proposed radical resection of gastric cancer (D1 or D2 lymph node dissection).
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. History of distant metastasis (stage M1) or other malignant tumors before surgery; 3. Combined with serious systemic diseases (such as severe liver and kidney insufficiency, active cardiovascular disease, etc.); 4. Combined with autoimmune diseases, infectious diseases or inflammatory states (may affect serum glycosylation status); 5. Severe hematological diseases or coagulation dysfunction; 6. Subjects have received any of the following anti-tumor treatments before blood collection: local or systemic chemoradiotherapy, targeted therapy (including anti-angiogenesis), immunotherapy, cancer vaccines, hormone therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lymph Node Metastasis Status;N-glycosylation Analysis Results; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age;Gender;Tumor size;Scope of operation;Mode of operation; | — |
Countries
China
Contacts
Public ContactGao Xiaodong
Department of General Surgery, Zhongshan Hospital, Fudan University School of Medicine
Outcome results
None listed