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Clinical application study of primary multi-neurovascularized latissimus dorsi muscle transplantation in the treatment of irreversible facial expression loss in children

Clinical application study of primary multi-neurovascularized latissimus dorsi muscle transplantation in the treatment of irreversible facial expression loss in children

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500108697
Enrollment
Unknown
Registered
2025-09-03
Start date
2024-10-10
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irreversible loss of facial expression

Interventions

Observation group:None

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age between 6-18 years old; 2. Able to tolerate medium-sized general anesthesia surgery; 3. History of complete facial paralysis for more than 3 years; 4. Facial nerve electrophysiological examination has objective criteria for facial muscle atrophy: loss of nerve potential; 5. Cured or stable primary disease; 6. Patients with tremor and small muscle laughter on the healthy side.

Exclusion criteria

Exclusion criteria: 1. Age less than 6 years old or greater than 18 years old; 2. Unable to tolerate large and medium-sized general anesthesia surgery; 3. The course of facial paralysis is less than 3 years; 4. Objective criteria for facial nerve electrophysiological examination without hemifacial muscle atrophy: loss of nerve potential; 5. The primary disease is unstable, and the tumor disease is stable for less than 5 years.

Design outcomes

Primary

MeasureTime frame
Whether facial expression recovered after surgery;

Countries

China

Contacts

Public ContactJi Kai

China-Japan Friendship Hospital

drjikai@outlook.com+86 10 84205224

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026