PONV,postoperative nausea and vomiting
Conditions
Interventions
Group T:Perioperative Use of Tegileridine for Analgesia
Group H:Perioperative Use of Hydromorphone for Analgesia
Sponsors
Zhongshan Hospital ( Xiamen ) , Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. 18 years = 3; 5. Voluntarily participate and provide signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe dysfunction of major organs (e.g., AV block above first degree without pacemaker, left ventricular ejection fraction <40%, coronary artery disease, myocardial infarction, hepatic or renal insufficiency, Parkinson's disease, Alzheimer's disease, seizure disorders, epilepsy); 2. Chronic pain (defined as pain persisting or recurring for more than 3 months); 3. Preoperative use of sedatives or analgesics (any sedative-hypnotic agents such as benzodiazepine and non-benzodiazepine receptor agonists, or opioid medications including morphine, fentanyl, and oxycodone); 4. Patients with known allergies to related drugs; 5. Patients unable to cooperate with postoperative follow-up or with communication barriers; 6. Pregnant or lactating women; 7. Patients with inadequate obtainment of medical history; 8. Patients who refuse to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of postoperative nausea and vomiting ; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of postoperative nausea and vomiting (PONV) ;The incidence of severe postoperative nausea and vomiting (PONV) and rescue treatments ;Postoperative analgesic efficacy ;Quality of Recovery (QoR) and Patient Satisfaction;Postoperative EQ-5D-3L Scores;Postoperative anesthetic complications; | — |
Countries
China
Contacts
Public ContactChao Liang
Zhongshan Hospital ( Xiamen ) , Fudan University
Outcome results
None listed