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Factors influencing corneal outcomes in patients with thyroid-associated ophthalmopathy and eyelid closure insufficiency after treatment

Factors influencing corneal outcomes in patients with thyroid-associated ophthalmopathy and eyelid closure insufficiency after treatment

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500108693
Enrollment
Unknown
Registered
2025-09-03
Start date
2025-09-03
Completion date
Unknown
Last updated
2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thyroid-associated ophthalmopathy and eyelid closure insufficiency

Interventions

Group with favorable corneal treatment outcomes:None
Group with unfavorable corneal treatment outcomes:None

Sponsors

The First Affiliated Hospital of Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Meets the diagnostic criteria for active orbitopathy (TAO) as outlined in the Chinese Guidelines for the Diagnosis and Treatment of Thyroid-Associated Ophthalmopathy (2022). 2.Presence of incomplete eyelid closure. 3.Throughout the treatment process, all patients underwent detailed corneal examinations both during their initial visits and throughout the follow-up period, with regular ocular assessments being conducted. 4.Complete case data and post-discharge follow-up records.

Exclusion criteria

Exclusion criteria: 1.Patients with thyroid-associated ophthalmopathy (TAO) who exhibit complete eyelid closure. 2.Patients with concomitant orbital space-occupying lesions, ocular trauma, or other ocular diseases. 3.Incomplete clinical data; 4.Patients unable to comply with post-discharge follow-up requirements.

Design outcomes

Primary

MeasureTime frame
The degree of eyelid closure;Smoking history;Course of the disease;Age;Hypercholesterolemia;

Countries

China

Contacts

Public ContactWang Xiaolei

The First Affiliated Hospital of Army Medical University

1921001@qq.com+86 23 68766242

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026