Double-Barreled Ileostomy
Conditions
Interventions
FMT group:On the day of intervention, collect 100 g of effluent from the proximal ileostomy, dilute it to 200–300 mL with sterile saline, and filter the mixture through two layers of sterile gauze to
Nacl group:Insert a 16-French three-lumen catheter approximately 10 cm into the distal limb of the loop stoma, inflate the balloon with 10–15 mL of sterile water, and then instill 200–300 mL of steril
Blank group:none
Sponsors
The First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Patients who underwent radical colectomy with terminal ileal loop stoma for malignant tumors of the left transverse colon, descending colon, sigmoid colon, and rectum. (2) Age 18–70 years. (3) BMI 18.5–23.9 kg/m². (4) Preoperative gastrointestinal contrast study and colonoscopy definitively excluding anastomotic leakage or obstruction.
Exclusion criteria
Exclusion criteria: (1) Having a history of alcohol abuse for more than 2 years and a long-term smoking history; (2) Have other metabolic diseases, such as obesity, hypertension, diabetes, calculus, various liver diseases, or have other autoimmune diseases, such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, etc; (3) Having a family history of genetics, mental illness, etc; (4) Researchers believe that other reasons are not suitable for continuing clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intestial barrier; | — |
Secondary
| Measure | Time frame |
|---|---|
| gut microbiota;Time to first postoperative flatus;time to first postoperative bowel movement;time to first formed stool;length of postoperative hospital stay;total hospitalization cost; | — |
Countries
China
Contacts
Public ContactQingliang He
The First Affiliated Hospital of Fujian Medical University
Outcome results
None listed