postpartum depression
Conditions
Interventions
observation group:None
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old and =34 weeks); 4. Voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.History of mental illness; 2.Uncontrolled hypertension, diabetes and heart disease; 3.Patients with severe preeclampsia and eclampsia; 4.Placental abruption, placental implantation; 5.Alcohol-dependent and drug-addicted individual; 6.Participant who refused to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of PPD 42 days postpartum; | — |
Secondary
| Measure | Time frame |
|---|---|
| Biomarkers such as venous blood, umbilical cord blood, and gut microbiota;Postpartum concentrations of melatonin and cortisol and their circadian rhythm parameters;Incidence of sleep - wake rhythm disorder on the 1st and 2nd days after delivery, before discharge, on the 7th and 42nd days after delivery;Hamilton Depression Score and Severity before Discharge, 7 Days Postpartum, and 42 Days Postpartum;NRS pain scores on the 1st and 2nd days after delivery and before discharge;EPDS scores before discharge, 7 days after delivery, and 42 days after delivery; | — |
Countries
China
Contacts
Public ContactLi Zhengqian
Peking University Third Hospital
Outcome results
None listed