ARDS
Conditions
Interventions
ARDS patients group :NA
Sponsors
The Second Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. ARDS (Berlin Definition): ARDS is an acute, diffuse, inflammatory lung injury; its main pathophysiological features include damage to pulmonary microvascular endothelium and alveolar epithelium caused by inflammatory responses, increased pulmonary microvascular permeability, exudation of protein-rich fluid into alveolar spaces, which further leads to pulmonary edema and hyaline membrane formation. In addition, it is accompanied by reduced lung volume, decreased lung compliance, and severe ventilation/perfusion mismatch. Inclusion criteria for ARDS patients (Berlin Definition): (1) Aged >= 18 years, regardless of gender; (2) Acute onset (= 5 cmH2O) - Mild: PaO2/FiO2 200–300 mmHg; - Moderate: PaO2/FiO2 100–200 mmHg; - Severe: PaO2/FiO2 = 18 years, regardless of gender; (2) Acute onset (= 30 L/min or non-invasive positive pressure ventilation/continuous positive airway pressure with positive end-expiratory pressure (PEEP) of at least 5 cmH2O, and meeting the ARDS hypoxemia criteria. ARDS in resource-limited settings: In resource-limited situations, a diagnosis can be made if SpO2/FiO2 = 18 years, regardless of gender; (2) No history of lung diseases. (3) No abnormalities found in routine examinations such as blood routine, blood biochemistry, coagulation function, electrocardiogram (ECG), and chest X-ray;
Exclusion criteria
Exclusion criteria: Patients or volunteers who are unable to cooperate or refuse to cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exhaled breath; | — |
Countries
China
Contacts
Public ContactXu Zhi
The Second Affiliated Hospital of Army Medical University
Outcome results
None listed