Chemotherapy-induced peripheral neuropathy in colorectal cancer patients
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The inclusion criteria of participants include CRC patients who (1) have received or currently receiving more than one cycle of oxaliplatin-based chemotherapy; and (2) experience CIPN symptoms; and (3) are able to use smart phone and WhatsApp; and (4) are able to read or understand Chinese.
Exclusion criteria
Exclusion criteria: CRC patients will be excluded from this study when they (1) received neurotoxic chemotherapy other than oxaliplatin, including taxane-based chemotherapy, vinca alkaloids, proteasome inhibitors and thalidomide analogs; or (2) suffer from severe organ failure or diseases that limit their level of activity; or (3) are diagnosed with non-chemotherapy induced peripheral neuropathy, such as sciatica and diabetic neuropathy; or (4) receive treatments that affect the severity of neuropathy, such as steroid, anticonvulsants and antidepressants; or (5) age below 18 years old; or (6) have cognitive impairments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chemotherapy-induced peripheral neuropathy 5:19 PM; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain;Quality of Life;Anxiety;Balance;Knowledge of exercise, exercise motivation and exercise self-efficacy;Adverse effects; | — |
Countries
China
Contacts
The Nethersole School of Nursing, The Chinese University of Hong Kong