Emergence Agitation
Conditions
Interventions
E Group:Esketamine 0.25 mg/kg was intravenously injected 10 minutes before the end of the surgery.
N1 Group:Nalbuphine 0.1 mg/kg was intravenously injected 10 minutes before the end of the surgery.
N2 Group:Nalbuphine 0.2 mg/kg was intravenously injected 10 minutes before the end of the surgery.
Sponsors
Shiyan People's Hospital
Eligibility
Sex/Gender
All
Age
3 Years to 7 Years
Inclusion criteria
Inclusion criteria: Children aged 3 to 7 years scheduled for elective adenotonsillectomy under general anesthesia were screened for eligibility. Inclusion criteria included American Society of Anesthesiologists (ASA) physical status I or II and a body mass index (BMI) between 12 and 24 kg/m^2
Exclusion criteria
Exclusion criteria: Exclusion criteria comprised known cardiovascular or pulmonary disease, a history of neurological or psychiatric disorders, allergy to any study drugs or anesthetic agents, recent upper respiratory tract infection, precious airway surgery, refusal of parental consent, or any intraoperative or postoperative event requiring deviation from the study protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of emergence agitation; | — |
Secondary
| Measure | Time frame |
|---|---|
| PAED score; | — |
Countries
China
Contacts
Public ContactZhangcheng Zou
Shiyan People's Hospital
Outcome results
None listed