lower urinary tract symptoms
Conditions
Interventions
patients with COPD AND LUTS:NA
patients with LUTS but not COPD:NA
Sponsors
The Second Affiliated Hospital of Guilin Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Requirements for diagnosing underlying diseases: Must meet the diagnostic criteria of the "Guidelines for Basic Diagnosis and Management of Chronic Obstructive Pulmonary Disease in China (2024)": (1) FEV1/FVC after bronchodilator is less than 0.7; (2) Persistent cough, expectoration or breathing difficulty symptoms; (3) Smoking history (>= 10 pack-years) or long-term exposure to harmful gases; (4) COPD clinical stage is GOLD 2-4 (moderate to severe). 2. Criteria for lower urinary tract symptoms: (1) International Prostate Symptom Score (IPSS) >= 8 points; (2) Persistent presence of at least one of the following symptoms for >= 3 months: (3) Storage phase symptoms: frequent urination (>= 8 times per day), urgency, nocturia (>= 2 times per night); (4) Urination phase symptoms: weak urine flow, hesitation in urination, intermittent urination; (5) Post-urination symptoms: incomplete urination sensation. 3. Requirements for imaging and urodynamic examinations: (1) Ultrasound shows residual urine volume in the bladder (PVR) >= 50 ml; (2) Urinary flow rate measurement Qmax = 150 ml).
Exclusion criteria
Exclusion criteria: 1. Those with a clear history of neurological disorders, mental disorders, and diabetes patients. 2. Patients diagnosed with neurogenic bladder. 3. Patients with a history of urethral stricture or urethral injury. 4. Patients with spinal cord injury, pelvic nerve injury, pelvic surgery history, radiotherapy history. 5. Patients with prostate cancer, bladder tumor, pelvic space-occupying lesion, ascites in abdominal cavity, and other conditions that affect the detrusor muscle pressure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bladder contractility index;maximum watt factor;post-voiding residual ;bladder obstruction index; | — |
Secondary
| Measure | Time frame |
|---|---|
| bladder wall thick ; | — |
Countries
China
Contacts
Public ContactNing Xiao
The Second Affiliated Hospital of Guilin Medical University
Outcome results
None listed